The Laboratory of Dr Xiaoyan Zheng in the Department of Anatomy and Cell Biology and the Cancer Center at the George Washington University School of Medicine and Health Sciences seeks a highly motivated Research Associate with backgrounds in cell biology. Our primary research interest is in identifying target genes regulated by the Hh signal and thus to understand the molecular mechanisms employed by the Hh signaling pathway in regulating cell-cell interactions (I). In parallel, we are interested in developing novel reagents and experimental approaches combined with cutting-edge imaging technologies to study the biochemical and cell biological principles governing a critical yet poorly understood step of Hh signal transduction: trafficking of Hh receptors (II). These studies have broad potential significance for our understanding of the molecular basis of both development and human diseases linked to Hh pathway dysfunction, as well as for providing a basis for therapeutic modulation of pathway activity, either positively to stimulate regeneration or negatively to block malignant growth.

This position independently carries out research/development activities by designing and conducting experiments in a controlled laboratory setting, under general guidance and supervision of the Principal Investigator. Using a certain degree of creativity and latitude, the core responsibilities of this position include making detailed observations, analyzing data, and interpreting results. This position compiles results and prepares technical reports and documentation of outcomes. This role is familiar with standard concepts, practices, and procedures within a particular field.

Duties include:

Background in Biology or Drosophila model is preferred.

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